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Opening ETF evidence benchSynchronizing prices, risk metrics, holdings coverage, and source lineage

Company research · XLV

Vertex Pharmaceuticals Incorporated

NASDAQ:VRTX

Pharmaceuticals: Major · attribution context sourced from stored price moves, stored event labels, and peer-relative residuals inside the XLV constituent company universe.

Open overview Open coverage audit Back to ETF companies

Attribution backlog

4high-priority unexplained moves

Market cap122B

Last close481.93

1M return-9.00%

Stored moves17

Stored price tapeDaily OHLC candles

+0.30%

Full history and event labels

May 13, 5:30 AM O 439.92 H 454.23 L 436.481 C 448.29 V 1398283, May 13, 9:30 PM O 446.47 H 455.32 L 444.26 C 453.06 V 1194366, May 14, 5:30 AM O 446.47 H 455.32 L 444.26 C 453.06 V 1194366, May 14, 9:30 PM O 453.64 H 456.68 L 447.36 C 450.41 V 1088448, May 15, 5:30 AM O 453.64 H 456.68 L 447.36 C 450.41 V 1088448, May 15, 9:30 PM O 453.45 H 453.45 L 435.86 C 436.95 V 1288893, May 16, 5:30 AM O 453.45 H 453.45 L 435.86 C 436.95 V 1288893, May 18, 9:30 PM O 435.42 H 440.04 L 430.25 C 436.58 V 1451054, May 19, 5:30 AM O 435.42 H 440.04 L 430.25 C 436.58 V 1451054, May 19, 9:30 PM O 436.79 H 444.32 L 433.15 C 434.31 V 1219660, May 20, 5:30 AM O 436.79 H 444.32 L 433.15 C 434.31 V 1219660, May 20, 9:30 PM O 434.31 H 439.98 L 427.6401 C 430.44 V 1784847, May 21, 5:30 AM O 434.31 H 439.98 L 427.6401 C 430.44 V 1784847, May 21, 9:30 PM O 429.36 H 434.76 L 426.01 C 433.54 V 1395240, May 22, 5:30 AM O 429.36 H 434.76 L 426.01 C 433.54 V 1395240, May 22, 9:30 PM O 437.07 H 438.84 L 432.96 C 434.52 V 1746340, May 23, 5:30 AM O 437.07 H 438.84 L 432.96 C 434.52 V 1746340, May 26, 9:30 PM O 437.99 H 441.99 L 433.79 C 435.93 V 865853, May 27, 5:30 AM O 437.99 H 441.99 L 433.79 C 435.93 V 865853, May 27, 9:30 PM O 438.52 H 445.35 L 435.3935 C 437.22 V 1164524, May 28, 9:30 PM O 434.08 H 449.29 L 434.08 C 447.97 V 1358231, May 29, 9:30 PM O 448.01 H 450 L 442.25 C 447.54 V 1893380, Jun 1, 9:30 PM O 439.91 H 443.54 L 433.2601 C 438.4 V 1115281, Jun 2, 9:30 PM O 432.4 H 434 L 424.9 C 425.09 V 1147095, Jun 3, 9:30 PM O 420.63 H 429.01 L 420.01 C 428.34 V 1564384, Jun 4, 9:30 PM O 434.95 H 448.19 L 433.5 C 441.74 V 1362422, Jun 5, 9:30 PM O 445.605 H 453.16 L 443.86 C 446.83 V 1530180, Jun 8, 9:30 PM O 443.17 H 448.6899 L 441.72 C 442.96 V 1149408, Jun 9, 9:30 PM O 447.02 H 449.5 L 440.9 C 445.77 V 871497, Jun 10, 9:30 PM O 447.27 H 447.5 L 433.8 C 435.71 V 1103240, Jun 11, 9:30 PM O 437.51 H 445.7799 L 435.21 C 445.04 V 1233868, Jun 12, 9:30 PM O 440.02 H 447.7 L 440.02 C 444.925 V 924189, Jun 15, 9:30 PM O 446.685 H 453.68 L 439.5 C 450.46 V 1482949, Jun 16, 9:30 PM O 452.82 H 454.55 L 444.215 C 453.17 V 1486576, Jun 17, 9:30 PM O 449.67 H 464.31 L 447.54 C 458.99 V 1524291, Jun 18, 9:30 PM O 462.17 H 464.98 L 450.39 C 451.63 V 2993021, Jun 22, 9:30 PM O 455.65 H 468.18 L 453.21 C 466.79 V 2034573, Jun 23, 9:30 PM O 469.67 H 470.82 L 463.755 C 468.42 V 1204019, Jun 24, 9:30 PM O 471.38 H 480.855 L 469.925 C 475.2 V 1549953, Jun 25, 9:30 PM O 475.11 H 486.485 L 473.5001 C 480.18 V 1522567, Jun 26, 9:30 PM O 482.5 H 503.89 L 482.2 C 491.34 V 8693047, Jun 27, 5:30 AM O 482.5 H 503.89 L 482.2 C 491.34 V 8693047, Jun 29, 9:30 PM O 495.83 H 499.87 L 487.62 C 499.65 V 2055780, Jun 30, 5:30 AM O 495.83 H 499.87 L 487.62 C 499.65 V 2055780, Jun 30, 9:30 PM O 500.49 H 500.99 L 489.62 C 496.73 V 1738335, Jul 1, 5:30 AM O 500.49 H 500.99 L 489.62 C 496.73 V 1738335, Jul 1, 9:30 PM O 502.71 H 502.71 L 494.8 C 498.01 V 1444535, Jul 2, 5:30 AM O 502.71 H 502.71 L 494.8 C 498.01 V 1444535, Jul 2, 9:30 PM O 503.76 H 529.14 L 501.53 C 528.04 V 1855943, Jul 3, 5:30 AM O 503.76 H 529.14 L 501.53 C 528.04 V 1855943, Jul 6, 9:30 PM O 526.665 H 529.9899 L 512.34 C 529.59 V 1515703, Jul 7, 5:30 AM O 526.665 H 529.9899 L 512.34 C 529.59 V 1515703, Jul 7, 9:30 PM O 530 H 533.67 L 512.77 C 522.25 V 2292906, Jul 8, 5:30 AM O 530 H 533.67 L 512.77 C 522.25 V 2292906, Jul 8, 9:30 PM O 523.04 H 525.81 L 498.14 C 498.43 V 2287222, Jul 9, 5:30 AM O 523.04 H 525.81 L 498.14 C 498.43 V 2287222, Jul 9, 9:30 PM O 495.58 H 500.77 L 482.11 C 496.5 V 2107282, Jul 10, 5:30 AM O 495.58 H 500.77 L 482.11 C 496.5 V 2107282, Jul 10, 9:30 PM O 498.15 H 498.91 L 484.33 C 485.39 V 1430390, Jul 11, 5:30 AM O 498.15 H 498.91 L 484.33 C 485.39 V 1430390, Jul 13, 9:30 PM O 486.175 H 486.175 L 474.71 C 480.25 V 1153856, Jul 14, 5:30 AM O 486.175 H 486.175 L 474.71 C 480.25 V 1153856, Jul 14, 9:30 PM O 481.285 H 481.285 L 473.18 C 476.31 V 1093659, Jul 15, 5:30 AM O 481.285 H 481.285 L 473.18 C 476.31 V 1093659, Jul 15, 9:30 PM O 472.15 H 480.96 L 469.6 C 477.08 V 1192070, Jul 16, 5:30 AM O 472.15 H 480.96 L 469.6 C 477.08 V 1192070, Jul 16, 9:30 PM O 480 H 487.3 L 476.25 C 486.03 V 1370959, Jul 17, 5:30 AM O 480 H 487.3 L 476.25 C 486.03 V 1370959, Jul 17, 9:30 PM O 483.51 H 496.69 L 481.975 C 485.65 V 1568122, Jul 18, 5:30 AM O 483.51 H 496.69 L 481.975 C 485.65 V 1568122, Jul 20, 9:30 PM O 485.65 H 491.23 L 478.48 C 480.5 V 1101762, Jul 21, 9:30 PM O 478.555 H 484.99 L 473.56 C 481.93 V 659438

From high -9.00%Drawdown -67.66%Stored labels 141

Price move attribution

Large moves, explained residuals, and research gaps

17 stored large-move attributions

High-priority unexplained moves4Open moves where direct company catalyst evidence is missing or weak.

Direct labels8Company-specific filings, disclosures, earnings, guidance, or direct source links.

Theme driver days0Moves benchmarked against a matched thematic basket before peer residuals.

Review workbench

High-priority unexplained moves

8 shown

Oct 15, 2020

No relevant stored event for down moveNo relevant stored event label passed the company move-attribution threshold for this -20.70% daily move. · Unexplained High Priority · generated

Move -20.70%Macro / market +0.12%Sector after macro -1.36%Industry after sector -0.74%Residual after context -18.71%

Review priority 100 · Source rank 0 · Volume 14.9x

Source gap missing_direct_company_catalyst · Next action research_company_specific_news

Decomposition: Macro +0.12% · Sector -1.36% · Industry -0.74% · Peer Specific +0.00% · Company Catalyst +0.00% · Unexplained Residual -18.71%

Dec 13, 2023

No relevant stored event for up moveNo relevant stored event label passed the company move-attribution threshold for this +13.23% daily move. · Unexplained High Priority · generated

Move +13.23%Macro / market +1.63%Sector after macro +0.13%Industry after sector -1.10%Residual after context +12.57%

Review priority 88 · Source rank 0 · Volume 4.3x

Source gap missing_direct_company_catalyst · Next action research_company_specific_news

Decomposition: Macro +1.63% · Sector +0.13% · Industry -1.10% · Peer Specific +0.00% · Company Catalyst +0.00% · Unexplained Residual +12.57%

Jun 11, 2021

No relevant stored event for down moveNo relevant stored event label passed the company move-attribution threshold for this -10.96% daily move. · Unexplained High Priority · generated

Move -10.96%Macro / market +0.42%Sector after macro -0.51%Industry after sector -0.32%Residual after context -10.55%

Review priority 83 · Source rank 0 · Volume 8.5x

Source gap missing_direct_company_catalyst · Next action research_company_specific_news

Decomposition: Macro +0.42% · Sector -0.51% · Industry -0.32% · Peer Specific +0.00% · Company Catalyst +0.00% · Unexplained Residual -10.55%

Dec 1, 2021

No relevant stored event for up moveNo relevant stored event label passed the company move-attribution threshold for this +9.66% daily move. · Unexplained Review · generated

Move +9.66%Macro / market -1.86%Sector after macro +1.63%Industry after sector +0.44%Residual after context +9.45%

Review priority 79 · Source rank 0 · Volume 3.4x

Source gap missing_direct_company_catalyst · Next action research_company_specific_news

Decomposition: Macro -1.86% · Sector +1.63% · Industry +0.44% · Peer Specific +0.00% · Company Catalyst +0.00% · Unexplained Residual +9.45%

Oct 28, 2022

Broad market moved +2.68% with this stockBroad market context explains +2.68 percentage points of the +9.03% daily move. Remaining company-specific residual is +8.45 percentage points and still needs direct catalyst coverage. · Context With Residual Review · macro

Move +9.03%Macro / market +2.68%Sector after macro -1.83%Industry after sector -0.27%Residual after context +8.45%

Review priority 72 · Source rank 54 · Volume 2.3x

Source gap missing_direct_company_catalyst · Next action research_company_specific_news

Decomposition: Macro +2.68% · Sector -1.83% · Industry -0.27% · Peer Specific +0.00% · Company Catalyst +0.00% · Unexplained Residual +8.45%

Mar 10, 2026

No relevant stored event for up moveNo relevant stored event label passed the company move-attribution threshold for this +8.31% daily move. · Unexplained Review · generated

Move +8.31%Macro / market -1.06%Sector after macro +1.25%Industry after sector +1.09%Residual after context +7.03%

Review priority 69 · Source rank 0 · Volume 2.3x

Source gap missing_direct_company_catalyst · Next action research_company_specific_news

Decomposition: Macro -1.06% · Sector +1.25% · Industry +1.09% · Peer Specific +0.00% · Company Catalyst +0.00% · Unexplained Residual +7.03%

Mar 13, 2020

Broad market moved +8.14% with this stockBroad market context explains +8.14 percentage points of the +8.23% daily move. Remaining company-specific residual is +6.76 percentage points and still needs direct catalyst coverage. · Context With Residual Review · macro

Move +8.23%Macro / market +8.14%Sector after macro -6.08%Industry after sector -0.59%Residual after context +6.76%

Review priority 67 · Source rank 54 · Volume 2.1x

Source gap missing_direct_company_catalyst · Next action research_company_specific_news

Decomposition: Macro +8.14% · Sector -6.08% · Industry -0.59% · Peer Specific +0.00% · Company Catalyst +0.00% · Unexplained Residual +6.76%

Mar 24, 2020

Broad market moved +10.27% with this stockBroad market context explains +10.27 percentage points of the +10.35% daily move. Remaining company-specific residual is +6.82 percentage points and still needs direct catalyst coverage. · Context With Residual Review · macro

Move +10.35%Macro / market +10.27%Sector after macro -4.63%Industry after sector -2.12%Residual after context +6.82%

Review priority 64 · Source rank 54 · Volume 1.1x

Source gap missing_direct_company_catalyst · Next action research_company_specific_news

Decomposition: Macro +10.27% · Sector -4.63% · Industry -2.12% · Peer Specific +0.00% · Company Catalyst +0.00% · Unexplained Residual +6.82%

Stored labels

Accepted price-move labels

10 shown

Date	Label	Move	Residual after context	Scope	Confidence
Oct 28, 2022	Broad market moved +2.68% with this stock	+9.03%	+8.45%	Macro	58%
Mar 13, 2020	Broad market moved +8.14% with this stock	+8.23%	+6.76%	Macro	58%
Mar 24, 2020	Broad market moved +10.27% with this stock	+10.35%	+6.82%	Macro	58%
Mar 16, 2020	Broad market moved -12.04% with this stock	-9.55%	-5.23%	Macro	58%
Aug 5, 2025	Vertex Pharmaceuticals Incorporated 10-Q: 10-Q	-20.60%	+0.67%	Direct	70%
Aug 5, 2025	Vertex Pharmaceuticals Incorporated 8-K: 8-K	-20.60%	+0.67%	Direct	70%
Aug 5, 2025	NASDAQ:VRTX quarterly report filing	-20.60%	+0.67%	Direct	94%
Dec 19, 2024	Vertex Pharmaceuticals Incorporated 8-K: 8-K	-11.37%	-0.96%	Direct	70%
Dec 19, 2024	NASDAQ:VRTX 8-K current report items 7.01	-11.37%	-0.96%	Direct	94%
May 6, 2025	Vertex Pharmaceuticals Incorporated 10-Q: 10-Q	-10.03%	-2.28%	Direct	70%